WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for each enriched gene sets are listed in this table.
For each gene set, the first row lists database name, gene set name , and corresponding gene set ID.
The second row lists the following statistics:
Finally, genes in the pathway are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:KEGG pathway       Name:Wnt signaling pathway       ID:04310
C=150; O=4; E=0.13; R=31.95; rawP=7.59e-06; adjP=4.55e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000139174 NA PRICKLE1 prickle homolog 1 (Drosophila) 144165 ENSG00000139174
2  ENSG00000104332 NA SFRP1 secreted frizzled-related protein 1 6422 ENSG00000104332
3  ENSG00000143816 NA WNT9A wingless-type MMTV integration site family, member 9A 7483 ENSG00000143816
4  ENSG00000157240 NA FZD1 frizzled family receptor 1 8321 ENSG00000157240


Database:KEGG pathway       Name:Phototransduction       ID:04744
C=29; O=2; E=0.02; R=82.62; rawP=0.0003; adjP=0.0009
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000133256 NA PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta 5158 ENSG00000133256
2  ENSG00000138472 NA GUCA1C guanylate cyclase activator 1C 9626 ENSG00000138472


Database:KEGG pathway       Name:Basal cell carcinoma       ID:05217
C=55; O=2; E=0.05; R=43.56; rawP=0.0010; adjP=0.0020
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000143816 NA WNT9A wingless-type MMTV integration site family, member 9A 7483 ENSG00000143816
2  ENSG00000157240 NA FZD1 frizzled family receptor 1 8321 ENSG00000157240


Database:KEGG pathway       Name:Pathways in cancer       ID:05200
C=326; O=3; E=0.27; R=11.02; rawP=0.0025; adjP=0.0037
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000143816 NA WNT9A wingless-type MMTV integration site family, member 9A 7483 ENSG00000143816
2  ENSG00000156427 NA FGF18 fibroblast growth factor 18 8817 ENSG00000156427
3  ENSG00000157240 NA FZD1 frizzled family receptor 1 8321 ENSG00000157240


Database:KEGG pathway       Name:Melanogenesis       ID:04916
C=101; O=2; E=0.08; R=23.72; rawP=0.0032; adjP=0.0038
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000143816 NA WNT9A wingless-type MMTV integration site family, member 9A 7483 ENSG00000143816
2  ENSG00000157240 NA FZD1 frizzled family receptor 1 8321 ENSG00000157240


Database:KEGG pathway       Name:Jak-STAT signaling pathway       ID:04630
C=155; O=2; E=0.13; R=15.46; rawP=0.0075; adjP=0.0075
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000114737 NA CISH cytokine inducible SH2-containing protein 1154 ENSG00000114737
2  ENSG00000120833 NA SOCS2 suppressor of cytokine signaling 2 8835 ENSG00000120833




WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).